Tuesday, August 6, 2019
The Rime of the Ancient Mariner Essay Example for Free
The Rime of the Ancient Mariner Essay 1. How do youà explain the Marinerââ¬â¢s killing of the albatross? I would describe the Marinerââ¬â¢s killing of the albatross as very ungrateful. If the albatross had not come along, the entire crew would have most likely died in the ice field. The Mariner was completely senseless in shooting the albatross; therefore, of course there was going to be very bad consequences. The consequences tend to be even worse than death at some points. The albatross did the Mariner and his crew a favor, by saving their lives, and the Mariner ungratefully shoots and kills his own savior. The lonely sailors treat the albatross like a person, a ââ¬Å"Christian soul.â⬠In Christian symbolism, Christ is sometimes metaphorically compared to a bird; hence, the albatross can be a symbol for Christ. Since the Mariner senselessly shot the albatross, he was persecuted, which is why the rest of his trip did not go very well. The poem describes the bird as a holy thing ââ¬Å"hailed in Godââ¬â¢s name.â⬠The Mariner is like the Christian who commits sins, causing Christ to die on the cross. Itââ¬â¢s Godââ¬â¢s rules that Man should respect all of His creations; the albatross is part of Godââ¬â¢s creations. In respecting the albatross, the Mariner would be respecting God himself. Furthermore, if the Mariner decided to respect God, and his creations, he may have had a better remainder of a trip. 2. One literary critic has said that the poem begins in despair and ends in hope. Telling the tale leaves the Mariner ââ¬Å"freeâ⬠for a time. Another critic has called the Mariner ââ¬Å"the voice of experience that transcends what man can learn in space and time.â⬠Discuss the validity of these ideas in relation to the poem as you understand it. Lastly, connect the theme of redemption to another literary work we have studied. 3. The idea of oneââ¬â¢s life beginning in despair and ending in hope reflects the idea of redemption. The mariner begins the poem in despair and guilt after he has killed the sacred albatross. The guilt is present in both the natural and the super natural world and is clearly depicted in the albatross that hung around his neck. It is not until the mariner appreciates both nature and prayer that he has found the road to redemption. The mariner is condemned to a life in death situation placing him in a different world than everyone else. He teaches us through space and time in his new form of living. He learns from his sins and searches for the path of redemption. The Christian allegory shows the bridge between the idea of fate being chosen for you and the ability to redirect fate. Like in The Scarlett Letter, Hester Prynn was searching for redemption from the sin she committed. She was forced into another world in which no one could quite understand. She had to overcome the judgments of another society and achieve her redemption in which she found in the natural world, her house in the woods, and the supernatural world, he redemption with God. 4. One scholar believes the Wedding Guest is chosen because he represents ââ¬Å"unsophisticated innocence preoccupied with pleasures of the moment in a universe of whose full dimensions and population he is quite ignorant.â⬠As a result of hearing the Marinerââ¬â¢s tale, the Wedding Guest changes, becoming ââ¬Å"a sadder and wiser man.â⬠Of what has he been forlorn (deprived)? Address this criticism in light of your understanding of Coleridgeââ¬â¢s narrative. I believe that the Wedding Guest becomes, in a sense, under the possession of the Mariner. The wedding-guest sat on a stone,/He cannot choose but hear;/And thus spake on that ancient man,/The bright-eyed mariner (Rime 1.17-20). The Mariner even refers to the guest as immature when he says that he ââ¬Å"listens like a three years child.â⬠After the Marinerââ¬â¢s story comes to an end, it is affirmed that the Wedding Guest has taken in knowledge that dramatically changes him as a human. He went like one that hath been stunned/And is of sense forlorn:/A sadder and a wiser man,/He rose the morrow morn (Rime 7.622-625). I believe that the Wedding Guest is the type of person who tends to take everything in his life for granted; hence, he wanted a change in his routine life. This story was one of the many instances that changed a person. I definitely see this as a point of reflection in his life, of what his life used to be. It can also be seen as a prevention to change his way of thinking before it becomes much too late.
Monday, August 5, 2019
Business Environment For Toyota Motor Corporation
Business Environment For Toyota Motor Corporation Business environment is about exploring the nature of the business in which it is being carried out. In this essay, analysis is being made for an automobile company known as Toyota Motor Corporation. Toyota Motor Corporation is commonly known as TOYOTA and is abbreviated as TMC. The company was founded by Kiichiro Toyoda in 1937 as a derivative from his fathers company Toyota industries to create automobiles. First passenger car was Toyota AA. Toyota Motor Corporation group companies are Toyota (including the Scion brand), Lexus, Daihatsu and Hino Motors, along with several non-automotive companies. Toyota Motor Corporation uses two tools for its business environment which is PEST and SWOT. Every business has an internal and an external environment. Before debating on external forces, internal forces/environment should be made clear. Internal environment is the one which is owned and controlled by the organisation itself. It comprises of: Resources: Toyota has a wide variety of resources such as well qualified employees, infrastructure. Knowledge and the actions of decision makers: As they have well qualified employees, Toyotas decision makers are successful decision makers. External Business environment is a set of political, economic, social and technological forces. These forces can have a negative as well as positive impact on the operation of a business. External factors are of two types (i) External Micro factors, and (ii) External Macro factors. External micro factors comprises of suppliers, agents, transporters, distributors, wholesalers etc. External macro factors comprises of Political, Economic, Social and Technological factors. External micro factors or industry factors can be influenced by an organisation whereas; External macro factors cannot be influenced by an organisation. Before beginning the marketing process, it is very important for an organisation to consider its external macro environment. External macro factors comprise of PEST factors as discussed above. PEST factors are explained below: Political: Political factor involve political stability, legal obligations for contract, intellectual property protection, trade regulations and tariffs, pricing regulations, taxation, wage legislation, product labelling requirements, environmental regulations. In 2004, Toyota spent $2.4 million (approx.) on lobbying. In 2005, its lobbying investment increased to $3.4 million and also for the first time TMC considered on creating a political committee. One strong factor behind Toyotas quest of greater political clout may be the possibility that the Big Three, staggered by slumping sales, will ask Congress for subsidies or a bailout, said Joan Claybrook, the president of the Public Citizen watchdog group in Washington. Economic: These factors comprise of Government intervention in the free market, infrastructure quality, inflation rate, interest rate, economic growth rate, availability of labour, wage rate of labour. Toyota got a tax incentive on producing clean fuel and hybrid engine cars. Due to this tax rebate on Toyota, purchasing parity of consumers was increased for expensive hybrid engine and clean fuel cars. Social: Social factors involve education, class structure, demographics, culture etc. Toyota has always remained one step ahead to its competitors. Toyota believes in sustainable development and they have proved it by producing clean fuel and hybrid engine cars. These cars ensure safety, better environment and affordability to their customers. Technological: These factors depend on a countrys technological knowhow, recent technological advancements, rate of technological diffusion, investments made by the company etc. Toyota invests millions of dollars an hour to improve their technology for better driving experience as well as for the safety of passengers. Toyota also managed to bag some awards for their safety systems installed in the car, which is again possible due to advanced technology. Advantages of PEST analysis: PEST analysis is an effective and efficient tool, which provides a framework to an organisation for effective decision making. By making effective use of PEST analysis, one can ensure affirmative orientation of the business organisation. PEST analysis also helps an organisation in avoiding decisions which should not be taken. PEST analysis helps in making lawful decisions for the companies which are willing to enter into a new market. Disadvantages of PEST analysis: PEST analysis considers only the external business factors, but in reality all the factors should be considered in order to make effective decisions for an organisation. Most of the data gathered through this analysis is based on assumptions, which sometimes may not prove to be fruitful for an organisation. The rapid changes in the world economy can also make it difficult in analysing PEST factors for an organisation. The second tool used by TMC, the SWOT analysis is discussed below: SWOT analysis helps an organisation in achieving their goals in the environment in which they are operating. It comprises of environmental factors such as Strengths, weaknesses, opportunities and threats. An explanation of these factors in context to TMC is discussed below: Strengths: Strength can be the expertise of an organisation. This attribute is internal to an organisation and can be controlled by it. Toyota made new investments in USA and China; subsequently their profits were also increased. This increase in the profits was due to the effective market segmentation which Toyota made. Toyota uses marketing techniques to find the needs of their target customers, the profits are also maximised by using effective manufacturing techniques. Weaknesses: Weaknesses of a company could be lack of effective marketing techniques, location of business, poor reputation etc. In Toyotas case, the weakness is the economic and political conditions of the countries in which it manufactures the largest number of cars. The demand for cars in USA and Japan is very fluctuating, this is the reason Toyota is making a shift toward emerging economies like China. Opportunities: An organisation can have many opportunities such as; mergers and acquisitions, availability of internet through which marketing becomes much easier, a new market segment, advance technology etc. Toyota has an opportunity of advanced technology, a new market segment and the availability of internet. By using advanced technology they produced hybrid cars, they got a new market segment in the name of Youth and they advertise their models on the internet. Threats: Threats can be minor manufacturing defects which can hamper the reputation of a company, price wars with competitors, new innovative product with the rival etc. Toyota has a threat in terms of both manufacturing defects as well as price wars. In 2005, Toyota had to recall a large number of vehicles due to faulty front wheel suspension system. And in USA, Toyota is facing tuff competition with General Motors. Advantages of SWOT analysis: One of the major advantages of SWOT analysis is that it provides a clear view of all the opportunities and issues being faced by an organisation. SWOT analysis also helps an organisation in saving time. SWOT analysis is very easy to perform; any employee with basic understanding can perform it efficiently. Disadvantages of SWOT analysis: SWOT analysis requires further thorough research in order to get a more comprehensive picture. For example, a business must consider the degrees of strengths, weaknesses, opportunities and threats. Sometimes, an organisation tends to miss the weaknesses after looking at the strengths. A thorough SWOT analysis should also see the opportunities available to a company in relation to strengths and weaknesses. SWOT analysis is an informal method which provides just an overview of the current market situation of a company.
Sunday, August 4, 2019
Essay --
1. Issues creating conflict in the scenario. Conflict refers to struggle or ideological differences between at least two or more parties, who have different tastes, perceive incompatible goals and objectives, scare resources and interference from others in achieving their desire. Issues that create conflict between Jim and Sarah in the scenario are their individual taste and preference. The two share work space and whereas Jim prefers listening to radio while he works, Sarah prefers very quite environment and the radio is a likely of destruction to her. Another cause of conflict is that Jim is very bossy and proud. Despite the fact that the two are employed to perform equal task of maintaining databases, Jim always feel that he is too senior in the organization and he makes very unique contributions to the organization. In this, he disregards Sarahââ¬â¢s contribution that does similar job like him. Another cause of conflict is that Saraââ¬â¢s is interested at changing the dynamics of the work to enhance her performance, and Jim is rigid about changing the dynamics and does not provide any working solution to the conflict. Sarah and Jimââ¬â¢s conflict management style Various people have different styles of managing conflicts in work places. These styles include, compromise, competition, accommodation, avoidance and collaboration. It is true that Sarah and Jim have different ways of managing the conflicts between the two of them. This diversity in conflict management styles between the two persons can be justified in the following ways; Sarahââ¬â¢s conflict management style Sara initially prefers accommodation style. She fears clashing with Jim over his behaviors and instead continues working in the noisy environment though she shows discomfort... ...em, he has never been involved in any scandal. In conclusion, it is true to say that Benjamin is an authentic leader because through his leadership, he has been able to diagnose problems and give the best course of action to solve the problem. Through his focus and charismatic leadership, he has been able to yield a lot of influence and power within the public and the political class. 3.Lessons that I can I take from Benjamin Bernankeââ¬â¢s leadership Benjamin is a very successful leader and a man who yields influence because of his hard work and determination. These are virtues that I would really love to use especially when I become a leader. I would love to provide amicable solutions to societal problems and leave legacy as an authentic leader who can easily be of help during crisis just like Benjamin during the economic crisis in 2008.
Saturday, August 3, 2019
The Factors Leading to Harryââ¬â¢s Demise in Oââ¬â¢Connorââ¬â¢s The River :: Oââ¬â¢Connor The RiverÃÂ
The Factors Leading to Harryââ¬â¢s Demise in Oââ¬â¢Connorââ¬â¢s The Riverà à à à à à à à à à à In Oââ¬â¢Connorââ¬â¢s story The River a young boy takes his own life in order to travel to the Kingdom of Christ. The boy lacks structure in his life, is neglected, and is bored. He lives with his parents in an apartment in a "city that rose like a cluster of warts on the side of the mountain". (P.35) There is not one particular incident that leads him to "baptise himself" (p.45), but a conglomeration of many. From his apartment and his parents, to his treatment as an adult, the only place in which he can find sanctuary is in the River of Christââ¬â¢s blood. His new faith paired with his longing for acceptance is what will ultimately led to Harry Ashfieldââ¬â¢s demise. Descriptions of the apartment throughout the story introduce the reader to the world in which this young boy lived in. In the beginning of the story the reader is told of how the apartmentââ¬â¢s air is stale with the smell of smoke. It is so bad that Mrs. Connin tells Harry that she will not be able to visit him in the apartment if she has to "smell those dead cigarette butts long". (p. 24) Yet another "flaw" Mrs. Connin addressed in the apartment is the picture on the wall. It is full of "black lines crossing into broken planes of violent color". (p. 24) The abstract picture in the apartment is symbolic of the life that Harry lead. He lives in a chaotic world without much guidance or many rules. Harryââ¬â¢s life up to the point of meeting Mrs. Connin lacks structure. The very fact that the family lives in an apartment rather than a house represents a lack of permanence. There is no commitment when living in an apartment. There is no mortgage to pay or yard to tend to. Because Harry had lived in this world of concrete for probably all of his life he has never really experienced nature. Nature represents permanence in a world that is anything but. When he was walking with Mrs. Connin down to the river, he walks through the paths as if heââ¬â¢s "never been in the woods before". (p.32) Nature is preferable to an urban setting and a character that is not one with nature can be seen as lacking. This lacking is visible in Harry throughout the story. The Factors Leading to Harryââ¬â¢s Demise in Oââ¬â¢Connorââ¬â¢s The River :: Oââ¬â¢Connor The Riverà The Factors Leading to Harryââ¬â¢s Demise in Oââ¬â¢Connorââ¬â¢s The Riverà à à à à à à à à à à In Oââ¬â¢Connorââ¬â¢s story The River a young boy takes his own life in order to travel to the Kingdom of Christ. The boy lacks structure in his life, is neglected, and is bored. He lives with his parents in an apartment in a "city that rose like a cluster of warts on the side of the mountain". (P.35) There is not one particular incident that leads him to "baptise himself" (p.45), but a conglomeration of many. From his apartment and his parents, to his treatment as an adult, the only place in which he can find sanctuary is in the River of Christââ¬â¢s blood. His new faith paired with his longing for acceptance is what will ultimately led to Harry Ashfieldââ¬â¢s demise. Descriptions of the apartment throughout the story introduce the reader to the world in which this young boy lived in. In the beginning of the story the reader is told of how the apartmentââ¬â¢s air is stale with the smell of smoke. It is so bad that Mrs. Connin tells Harry that she will not be able to visit him in the apartment if she has to "smell those dead cigarette butts long". (p. 24) Yet another "flaw" Mrs. Connin addressed in the apartment is the picture on the wall. It is full of "black lines crossing into broken planes of violent color". (p. 24) The abstract picture in the apartment is symbolic of the life that Harry lead. He lives in a chaotic world without much guidance or many rules. Harryââ¬â¢s life up to the point of meeting Mrs. Connin lacks structure. The very fact that the family lives in an apartment rather than a house represents a lack of permanence. There is no commitment when living in an apartment. There is no mortgage to pay or yard to tend to. Because Harry had lived in this world of concrete for probably all of his life he has never really experienced nature. Nature represents permanence in a world that is anything but. When he was walking with Mrs. Connin down to the river, he walks through the paths as if heââ¬â¢s "never been in the woods before". (p.32) Nature is preferable to an urban setting and a character that is not one with nature can be seen as lacking. This lacking is visible in Harry throughout the story.
Friday, August 2, 2019
dark side :: essays research papers
ââ¬Å"THE DARK SIDEâ⬠à à à à à Sara was a 15 year old girl who had just moved into new town with her mom. Her parents got divorced and she was taking it very hard. She missed all her friends and family she left back home and she felt out of place. All she wanted is her old life back and be happy like she used to be. But that was impossible and she just had to deal with the situation. à à à à à She started her first year of high school and she hated it. She didnââ¬â¢t fit in with the crowd, the teachers picked on her, and her grades were poor. She gave up on her hobbies, like sports, and drawing; things that she enjoyed doing. In other words, she became depressed. Spending all her time daydreaming of a better life, during the night, she stayed up and cried. She felt so lonely, wanting to escape to a far off place. à à à à à As those terrifying days passed, she met this group of kids. Others didnââ¬â¢t like them because of their gothic ways. Kids were scared of them, and became known as the outcasts. Sara became acquainted with them fast. They started to hang out more, she felt comfortable around their presence. She also started to like the activities they did like spells, witchcraft, rituals, and ceremonies that took place at the cemetery. She was fascinated and glad that she found her spiritual side. à à à à à She automatically changed. She became this unknown person. Her mother and the people around her noticed that she became weird. But she enjoyed what she did, because it gave her a sense of power and control over her life. Although, what she didnââ¬â¢t know was that the witchcraft became her obsession. She stared to get more involved in it. Now not only did she did spells, Voo Doo Dolls, and rituals but she started ââ¬Å"Black Magicâ⬠. Which is very dangerous, and it might even cause disaster. Her habits got so out of hand that even the crowd didnââ¬â¢t want to hang around with her, because they were afraid to mess with Black Magic. Sara believed so strongly in the evil powers that she decided to invoke the evil spirit. à à à à à At midnight, she went to the cemetery all by herself. She made a fire and drew the devil stars around it with human blood. She kneeled down in front of the burning fire, holding the black book in her hands, she said the following words ââ¬Å"EVIL SPIRIT COME TO ME, I INVOKE THEEâ⬠, and she threw a mixture into the flames.
Anaemia
Abstract Background: Anaemia is common worldwide specially in developing countries where nutrient deficiencies are prevalent. It is a common problem in the outpatient set but itââ¬â¢s always neglected and taken lightly which can cause hyperdynamic circulation disturbances and raise the rate of morbidity and mortality. Aim: To determine the prevalence of microcytic Hypochromic anaemia in medicine emergency room casualty in academy teaching hospital. Method: This is a descriptive cross-sectional study which was done in the Academy Teaching Hospital in which 75 of the emergency room patients participated in the study.The state of nutrition of the patients was evaluated by a questionnaire answered by the patients. Chapter One Introduction and Literature Review 1. 1 Introduction Anaemia Anaemia is defined as the reduction in the oxygen-transporting capacity of blood, which usually stems from a reduction of the total circulating red cell mass to below normal amounts. Blood haemoglobi n level is below 13. 5 g/dl in an adult male and below 11. 5 g/dl in an adult female. (1) Classification: Classified according to: 1. Causes: a. Inadequate production of RBC. b. Blood loss anaemia: * Acute: due to acute hemorrhage. * Chronic: due to GIT bleeding, menorrhagia. . Excessive destruction of RBC (haemolysis). 2. Morphology: a. Microcytic: * Iron deficiency. * Thalassemia. * Sideroblastic. b. Microcytic: * Folate deficiency. * B12 deficiency. c. Normocytic: * Aplastic anaemia. * Myelodysplastic anaemia. There are many undiagnosed cases of anaemia that if left undetected can lead to several complications, those include: (2) 1. Infections: people with the anaemia are more susceptible to getting infections from viruses and bacteria. 2. Severe bleeding: if bleeding is severe, internal and excessive then death can ensue if a blood transfusion is not given and the cause of the bleeding is not treated. . Stroke: if haemoglobin is defective, it can damage the walls of the red bloo d vessels and this can result in narrowing or even blockages in the brain, which can lead to serious, life threatening strokes. (2) Microcytic Hypochromic Anaemia Microcytic anemia is a blood disorder characterized by small red blood cells (erythrocytes) which have insufficient haemoglobin and hence have a reduced ability to carry oxygen through the body. The red blood cells are small due to a failure of haemoglobin synthesis or insufficient quantities of haemoglobin available. (3) Classification: 1. Iron deficiency anaemia . Sideroblastic anaemia. 3. Thalassemia. Iron deficiency anaemia Itââ¬â¢s estimated to be the main cause of anaemia affecting about 10% of the population in developed countries and 25-50% in developing countries. The prevalence of iron deficiency anemia in the United States was 2 percent in adult men, but was found to be more common in child-bearing women age. (4) Total body iron content is about 2gm for females, and 6gm for males. Most of the iron within the body is found in hemoglobin within erythrocytes (80%), with the remainder being found in myoglobin and iron containing enzymes.Iron is stored in liver, spleen, bone marrow and skeletal muscle. This iron storage pool contains on average 15-20% of total body iron. (4) Iron is transported in the plasma by an iron binding protein called transferrin. In normal individuals, transferrin is about 33% saturated with iron. Dietary iron is obtained either from inorganic sources or animal sources. Dietary iron enters intestinal cells via specific transporters. The iron is then used by the cell, stored as ferritin or transferred to the plasma. (4) Erythropoiesis is the development process in which new erythrocytes are produced, through which each cell matures in about 7 days.Through this process erythrocytes are continuously produced in the red bone marrow of large bones, at a rate of about 2 million per second in a healthy adult. The blood's red color is due to the spectral properties of the he mic iron ions in hemoglobin. The red blood cells of an average adult human male store collectively about 2. 5 grams of iron, representing about 65% of the total iron contained in the body. (5)(6) Causes: * Poor intake. * Decreased absorption (celiac disease, gastrectomy). * Increased demand in growing adolescents and pregnancy. * Blood loss from GIT due to: * Hookworm infestation. Erosions associated with NSAID, peptic ulcer or neoplastic disease. * Hemorrhoids. * Blood loss from irregular or excessive menstruation. Symptoms and signs (7) Symptoms may include: * Fatigue. * Shortness of breath * Lightheadedness. * Palpitations. * Dizziness. * Chest pain. * Blurred vision. * Sleep disturbance. Signs may include: * Rapid heart rate. * Low blood pressure. * Rapid breathing. * Pale conjunctiva. * Cold skin. * Enlargement of the spleen. Diagnosis of iron deficiency anaemia: * Complete blood count and color: with iron deficiency anaemia red blood cells are smaller and paler in color than n ormal. Hematocrit: This is the percentage of blood volume made up by red blood cells. Normal levels are generally 41% for adult women and 47% for adult men. These values may change depending on your age. * Haemoglobin: Lower than normal hemoglobin levels indicate anemia (12-16 g/dl in an adult male and 13. 7-17. 5 g/dl in an adult female). * Ferritin: This protein helps store iron in your body, and a low level of ferritin usually indicates a low level of stored iron. Some tests might be done to detect the underlying cause, like: * Endoscopy: Often to check for bleeding from a hiatal hernia, an ulcer or the stomach. Colonoscopy: To rule out lower intestinal sources of bleeding. * Ultrasound: Women may also have a pelvic ultrasound to look for the cause of excess menstrual bleeding, such as uterine fibroids. (8)(9) Sideroblastic anaemia It is a disease in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). [10] In Sideroblastic anemia , the body has iron available but cannot incorporate it into hemoglobin, which red blood cells need to transport oxygen efficiently.Sideroblasts are atypical, abnormal nucleated erythroblasts (precursors to mature red blood cells) with granules of iron accumulated in perinuclear mitochondria. [11] Sideroblasts are seen in aspirates of bone marrow. Causes: * Failure to completely form heme molecules, This leads to deposits of iron in the mitochondria that form a ring around the nucleus of the developing red blood cell. * Toxins: lead, copper or zinc poisoning * Drug-induced: ethanol, isoniazid, chloramphenicol, cycloserine, Oral Contraceptives * Nutritional: pyridoxine (Vitamin B6) or copper deficiency * Diseases: Rheumatoid arthritis, or multiple myeloma Genetic: ALA synthase deficiency (X-linked, associated with ALAS2)[12] Symptoms and signs: * Pale skin, eyelids and lips. * Fatigue and weakness. * Dizziness. * Enlarged liver and/or spleen. Diagnosis: Ringed sideroblasts are seen i n the bone marrow. Laboratory findings: * Increased ferritin levels * Normal total iron-binding capacity * Hematocrit of about 20-30% * Serum Iron: High * High transferrin saturation * The mean corpuscular volume or MCV is usually normal or low. * With lead poisoning, see coarse basophilic stippling of red blood cells on peripheral blood smear * Specific test: Prussian Blue stain of RBC in marrow.Shows ringed sideroblasts. * can also cause microcytic hypochromic anemia. (12) Thalassemia It is a group of inherited autosomal recessive blood disorders that originated in the Mediterranean region. In Thalassemia the genetic defect, which could be either mutation or deletion, results in reduced rate of synthesis, or no synthesis of one of the globins chains that make up hemoglobin. This can cause the formation of abnormal hemoglobin molecules, thus causing anemia, the characteristic presenting symptom of the Thalassemia. (13) Symptoms and signs: * Fatigue and weakness. * Shortness of brea th. * Pale appearance. Irritability. * Yellow discoloration of the skin. * Facial bone deformities. * Slow growth. * Abdominal swelling. * Dark urine. (14) Diagnosis: * Blood tests. * Prenatal screening. (14) Laboratory findings: * A low level of red blood cells * Smaller than expected red blood cells * Pale red blood cells * Red blood cells that are varied in size and shape * Red blood cells with uneven hemoglobin distribution, which gives the cells a bull's-eye appearance under the microscope. (14) 1. 2 Literature Review A study was done in Italy about prevalence and incidence and types of mild anaemia in the elderly.The objectives of this study were to estimate the prevalence and incidence of mild grade anemia and to assess the frequency of anemia types in the elderly. Design and Methods: This was a prospective, population-based study in all residents 65 years or older in Biella, Italy. Results: Blood test results were available for analysis from 8,744 elderly. Hemoglobin concent ration decreased and mild anemia increased steadily with increasing age. Mild anemia (defined as a hemoglobin concentration of 10. 0-11. 9 g/dL in women and 10. 0-12. 9 g/dL in men) affected 11. % of the elderly included in the analysis, while the estimated prevalence in the entire population was 11. 1%. Before hemoglobin determination, most mildly anemic individuals perceived themselves as non-anemic. Chronic disease anemia, Thalassemia trait, and renal insufficiency were the most frequent types of mild anemia. (15) A study was done in emergency ward, Mulago Hospital, Uganda. Anaemia is a common problem in Africa, with prevalence ranging from 21. 1% to 64. 4% 16-21 and a significant impact on morbidity and mortality. 22,23 in patients with AIDS low haemoglobin levels are associated with poor outcomes. 4-27 However, anaemia in Africa has multiple causes, with infectious diseases such as HIV, tuberculosis and malaria contributing significantly to the anaemia burden. 28 Hookworm is a major contributor to anaemia and even light hookworm loads are associated with low haemoglobin levels, 29-33 although Lewis et al. reported that hookworm was not a common cause of anaemia among medical patients in Malawi. In a cross-sectional descriptive study 395 patients were recruited by systematic random sampling and their socio-demographic characteristics and clinical details collected.A complete blood count and peripheral film examination were done and stool examined for hookworm ova.. Of the patients 255 (64. 6%) had anaemia. The prevalence was higher among males (65. 8%) than females (63. 7%). Fatigue (odds ratio (OR) 2. 1, confidence interval (CI) 1. 37 ââ¬â 3. 24), dizziness (OR 1. 64, CI 1. 07 ââ¬â 2. 44), previous blood transfusion (OR 2. 83, CI 1. 32 ââ¬â 6. 06), lymphadenopathy (OR 2. 99, CI 1. 34 ââ¬â 6. 66) and splenomegaly (OR 5. 22, CI 1. 78 ââ¬â 15. 28) were significantly associated with anaemia. Splenomegaly, low body mass index (BMI) (
Thursday, August 1, 2019
The Impact of Climate Change
In the last few years there has been a lot of attention given to the problem of climate change. Usually we only hear vague ideas about how the Earth is heating up, how we are all going to die and that we are to blame. However climate change is a natural process that experts have said has been sped up by human activity, for example, industrial activities, vehicles and machines producing gases like carbon dioxide and methane. These gases are damaging because of how the Sun's rays heat up the Earth. The rays from the Sun enter the atmosphere, hitting the Earth's surface with most being reflected back without heating up the Earth at all. The ones that are absorbed by the sea and the ground are reflected back as infrared rays therefore heating up the Earth. However as more CO2 and other ââ¬Å"greenhouse gasesâ⬠are pumped into the atmosphere, fewer and fewer of the Sun's rays are reflected away, hence the rising temperatures. Although there is debate over the largest contributor to the climate change problem that is not my focus for this essay. In this essay I intend to show how climate change would affect the world's water; that is to say 70% of the Earth's surface. The most talked about point in the media about the effect of climate change on water is the sea level. This is because as the Earth heats up the seas and oceans will absorb a lot of the heat causing the water molecules to expand and the sea level to rise. Another possible factor that contributes to the rising sea levels is the melting of the glaciers, ice shelves and ice sheets and this has another effect. As there is less and less ice to reflect back the sun's rays as ice reflects back 90% of the light that hits it while water absorbs the same percentage, this speeds up the warming of the earth even more and as more and more ice melts the problem worsens. There are many inter-linking consequences to the rising sea levels and of global warming. Droughts, floods and even the danger of the Gulf Stream, the warm water current that heats up our region, shutting down. The idea of flooding because of rising sea levels is self-explanatory. As there is more water, rivers, lakes and streams could break their banks and flood. The possibility of the Gulf Stream shutting down is more complicated and will have a much more lasting effect. The Gulf Stream works through a mixture of wind, water salinity and temperature, the shape of the ocean floor and the Earth's rotation. As temperatures continue to fall and more sea ice melts, this adds more fresh water to the Atlantic, reducing the salinity of the water. As there is less dense and less salty water, the Gulf Stream slows down. As it does slow down and weaken it will become more and more unstable and more likely to shut down altogether, lowering temperatures in our region by up to 9oC. Fortunately there are things we can do to help the climate change problem. Saving energy lowers the amount of fossil fuels that are needed to produce that energy and the less coal, oil and gas being burned in power plants, the lower the emissions of carbon dioxide. Saving energy can be a simple matter, such as switching off lights when you leave a room, having showers instead of baths, and turning down central heating systems, even 1oC can save up to 10% on energy bills. One of the most effective ways of helping is properly insulating your home as this reduces the energy needed to heat your home. The second most important greenhouse gas, methane is produced by landfill waste, which comprises 90% of the UK's sixteen million tonnes of waste each year. If we recycle more and more of this waste then there is less need to mine for raw materials and less methane being produced as there is less landfill waste. Two hundred years ago, if we produced the same amount of carbon dioxide as we did now, it probably would not have had any major effect, as there was not the same level as deforestation. The reason this would have made a difference is because trees take in carbon dioxide and produce oxygen. Although the effects of climate change won't be felt for years, we owe it to the future generations to save, if not our planet, our way of life.
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